BUY IBOGAINE CAPSULES
Ibogaine is a naturally occurring psychoactive substance found in plants in the Apocynaceae family, including Tabernanthe iboga, Voacanga Africana, and Tabernaemontana Undulata. It is a psychedelic with dissociative properties. Also called Bois Sacré, Eboka.
Effects Of Ibogaine
Ibogaine capsules and noribogaine interact with multiple neurotransmitter systems. They show a micromolar affinity for N-methyl-D-aspartate (MDMA), κ- and μ-opioid receptors, and sigma-2 receptor sites. It alters the expression of several proteins including substance P, brain-derived neurotrophic factor (BDNF), c-fos, and EGR-1.
CARDIOTOXICITY: Ether-a-go-go-related gene (hERG) potassium channels in the heart might play a crucial role in ibogaine’s cardiotoxicity, as hERG channels are vital in the repolarization phase of cardiac action potentials and blockade by Eboka delays this repolarization, resulting in QT (time interval between the start of the Q wave and the end of the T wave in the electrical cycle of the heart) interval prolongation and, subsequently, in arrhythmias and sudden cardiac arrest. However, this review presents 8 case reports which suggest that Eboka caused ventricular tachyarrhythmias and prolongation of the QT interval in individuals without any pre-existing cardiovascular condition or family history. Noribogaine appears at least as harmful to cardiac functioning as Bois Sacré.
Differences Between Iboga and Ibogaine
Iboga is used for and most often used amongst the Bwiti tribe for immersion in the deep religious and spiritual experience. With ibogaine, one is immersed within a compound of the whole and is most often used to heal addiction. Also rather than for religious or spiritual gain. Pure ibogaine tends to lead to more hyperactivity afterward, whereas iboga results in a more balanced state. Ibogaine is only one of eleven or more compounds found in the various iboga species.